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We have research studies available for adults with Bipolar Disorder. The purpose of these research studies is to find safer and more effective medications for individuals with Bipolar Disorder.

The investigational medication will be provided at no cost and compensation is provided for time and travel. No health insurance is required to participate in any of our Bipolar Disorder studies.

Bipolar Disorder Clinical Trials

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What is Bipolar Disorder?

Bipolar Disorder, also known as manic depression, is a brain disorder that causes extreme mood swings that include emotional highs (mania or hypomania) and lows (depression).

Common Mania Symptoms:

  • Feeling up, high, or elated

  • Having a lot of energy or feeling hyper

  • Feeling jumpy or wired

  • Talking a lot or talking fast

  • Feeling like your thoughts are going very fast

  • Having an increase in activity levels

  • Engaging in risky behaviors

  • Trouble sleeping 


Common Depression Symptoms:

  • Little interest or pleasure in doing things

  • Feeling down, depressed or hopeless

  • Trouble sleeping (too much or too little sleep)

  • Feeling tired or having little energy

  • Poor appetite or weight loss

  • Feeling bad about yourself

  • Feeling tense, edgy, anxious or nervous


When you become depressed, you may feel sad or hopeless and lose interest or pleasure in most activities. When your mood shifts to mania or hypomania (less extreme than mania), you may feel euphoric, full of energy or unusually irritable. These mood swings can affect sleep, energy, activity, judgment, behavior and the ability to think clearly.1

Adult bipolar disorder clinical trials

If you answer YES to all of the following questions then you may qualify for our adult Bipolar Disorder clinical trials.

1. Are you between the ages of 18-65 years old?

2. Do you currently have bipolar symptoms?

3. Are you willing to take study medication?

Final eligibility is determined during a screening visit at our study site at Orange. During this visit, you will:

  • Meet with a professional physician, psychiatrist, and/or psychologist and be interviewed about your mental and physical health

  • Review additional information

  • Undergo a physical examination and have your vitals taken

If you qualify and decide to participate:

  • A study doctor will closely monitor you, your symptoms, and overall health

  • All study-related medical care and study medication will be provided at no cost

  • Transportation may be provided at no cost if you need assistance

  • You will sign an Informed Consent Form (ICF) which outlines which procedures you can expect during each visit

  • You will be compensated for each completed visit

*A list of common procedures involved when participating in a clinical trial can be found here. Accessed April 23, 2019.

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